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KMID : 0371619990150020169
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Journal of Wonkwang Medical Science
1999 Volume.15 No. 2 p.169 ~ p.173
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The results of CLO test in the operative patients with gastric cancer and peptic ulcer
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Lee Jeong-Kyun
Lee Kyoung-Keun
Ann Jin-Hong
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Abstract
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Background: In 1983, Warren and Marshall presented the evidence that H. pylori was associated with gastritis and peptic ulcer. Thereafter, H. pylori infection is thought to be a important factor in the pathogenesis of gastric cancer and peptic ulcer. The aim of study was to investigate the relationships between CLO positivity and clinico-pathologic features in gastic cancers and peptic ulcer which was surgically resected.
Methods: Retrospective clinics-pathologic study was performed in 80 patients from 1998 to 1999. We performed the CLO tests in 63 patients with resected gastric cancer. Biopsy was done in 17 operative patients with peptic ulcer. Two specimens was taken from body and antrum of stomach.
Results: 1) The CLO positivity was 63.5% in resected gastric cancers and 64.7% in peptic ulcer which biopsy was done among the operation. But, there was no significant difference between two groups. 2) There was no significant difference of clinical features and CLO positivity in gastric cancers groups. 3) There was no significant difference of TNM classification and stage in CLO(+)(-)patients in gastric cancers group. 4) There was no significant difference of clinical features and CLO positivity in peptic ulcer groups.
Conclusions: The positive CLO tests was 64.7% in gastric ulcer, 87.5% in duodenal ulcer, and 63.5% in stomach cancer. There was no difference of CLO positive ratio in stomach cancer and peptic ulcer. There was no clinico-pathologic difference between CLO(+) and (-) gastric cancer.
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KEYWORD
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CLO test, gastric cancer, peptic ulcer
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